Well definatly I gotta say my 5 fav are:
1) Chrono Crusade... Saddest ending of any anime ever, eh? Cos-played as Chrono one time (no pics on this computer, remind me another time n I'll show you the costume!)
2) PeaceMaker Kurogane... This could have been my favourite, but it is my most recently completed series... Another rather-sad ending. Tetsu & Saya are one of my favourite charector-relationships ever!
3) Fruits Basket... Self Explanitory... Thats just simply the funniest Anime ever! Nothing Beats an Angry version of Kyo!
4) Vampire Knight... Even though they havent released an Anime of it yet (not to my knowledge at least) It is the best... Zero n Yuki are SO ment to be... gotta love a good gory-romance manga!
5) Nausica: Valley of the Wind.... While I thought the manga was MUCH better... the Anime still had its flare. A good Action-drama. A true Studio Ghibli film at its best.
Other favs include but are not limited to: Excel Saga, Akira, Afro Samurai, Negima, Midori Days & Mar (Havent seen the anime tho, only read Mar's mangas!)
I really dont like anime's that abondon the original story-line of the manga completly... I mean Akira as an example... In the anime They killed of the charectors and changed up the plot after the Volume 1 manga!!!
My Ex-GF got me into it. She was reading and watching all that sorts of stuff. Not the best topic because it brings back unwanted memories, but basically she loaned me her stash from time-to-time.
Hope thats good!