This game was fun, but it was time-consuming. All I can say is use similar strategies in Portal Defenders. Let your enemies fuck each other up first if you're having problems. You only need to win once as a real man, and it's VERY doable fighting ZOMG with his kickass spear. Don't forget to jump if you're getting stuck. It may even work on some repetitive boss attacks. From what I can tell, try and stay on the right (and possibly upper-half) when he spins.
You can get like three-four hits on Zomboss after he attempts to grab you (his shoulders move up), so you can just run back and forth and do this. He'll eventually jump after you take around half of his life out, but you just have to move around and hit three-four times. That's a general good amount to hit bosses in general. You can (no kidding) jump maybe once over SmileBorg's laser and you'll be safe. I jumped repetitively out of habit, but I eff'd up once, but his laser still didn't hit me. His level should also be doable as a real man.
It would be nice if there were other achievements, or an achievement that would force you to play the game without using your special attack or something. Otherwise, this game is fun, tedious, and probably needs Nazi's, Vampires, Werewolves, and AIDS. Or cancer.