Inferior
The original was better by a very long way, with a creepy atmosphere and a concentration on the virus, news reports adding a detached view of the human response on a global scale. The interactivity of the original was almost completely confined to modifying the virus and then sitting back and watching it spread in a fairly realistic way, killing the entire world. Like I said, creepy.
I get the impression that the creator of this spinoff didn't like the seeming randomness of the original and wanted to command his legions of germs in glorious warfare on humanity, but taking a more direct hand rather than modifying the virus and allowing it to go it's own insidious way has oversimplified the overall game experience. The division of the world population into ten little green men living on each subcontinent and the ability to send the virus across a border at will has drained all the realism, and thus the atmosphere, away.
One other small but very annoying thing - having greenland as a territory with the same population as south east asia, enforcing the arbitrary political border between the US and canada before the more relevant geographical barrier of the sahara desert... the poor geography also detracts from the realism.